Apparently, Johnny Depp can rule the box office in any shape or form, say as a lizard, a mad hatter or a pirate… however, not so much as Angelina Jolie’s potential lover. After suffering the disappointment of a lackluster showing from his last film The Tourist with Jolie, Depp is back on top with his new animated film Rango in which he plays a lizard, or a gecko to be more precise, as the movie took in a big $38 million over the weekend. That easily led the way despite a decent showing from the sci-fi romantic thriller The Adjustment Bureau starring Matt Damon and Emily Blunt which nabbed second place and nearly $21 million. That was an especially good showing considering the film has been on the release schedule 4 times over the last year or so (never a good sign). Also opening was the Vanessa Hudgens/Alex Pettyfer romance Beastly in third with a better than expected $10 million, and the comedy Take Me Home Tonight which tanked in 11th place garnering only $3.5 million. Take a look at the new box office top ten below and for more info, head to Box Office Mojo here.
| TW | LW | Title (click to view) | Studio | Weekend Gross | % Change | Theater Count / Change | Average | Total Gross | Budget* | Week # | |
| 1 | N | Rango | Par. | $38,000,000 | - | 3,917 | - | $9,701 | $38,000,000 | $135 | 1 |
| 2 | N | The Adjustment Bureau | Uni. | $20,945,000 | - | 2,840 | - | $7,375 | $20,945,000 | - | 1 |
| 3 | N | Beastly | CBS | $10,115,000 | - | 1,952 | - | $5,182 | $10,115,000 | $17 | 1 |
| 4 | 1 | Hall Pass | WB (NL) | $9,015,000 | -33.4% | 2,950 | - | $3,056 | $27,001,000 | $36 | 2 |
| 5 | 2 | Gnomeo and Juliet | BV | $6,912,000 | -48.4% | 2,984 | -53 | $2,316 | $83,694,000 | - | 4 |
| 6 | 3 | Unknown | WB | $6,620,000 | -47.3% | 2,913 | -130 | $2,273 | $53,129,000 | $30 | 3 |
| 7 | 8 | The King’s Speech | Wein. | $6,501,000 | -11.4% | 2,240 | -146 | $2,902 | $123,817,000 | $15 | 15 |
| 8 | 5 | Just Go With It | Sony | $6,500,000 | -38.3% | 2,920 | -624 | $2,226 | $88,200,000 | $80 | 4 |
| 9 | 4 | I Am Number Four | BV | $5,702,000 | -48.2% | 2,903 | -253 | $1,964 | $46,440,000 | $60 | 3 |
| 10 | 6 | Justin Bieber: Never Say Never | Par. | $4,325,000 | -53.9% | 2,254 | -556 | $1,919 | $68,876,000 | $13 | 4 |
